The uptake of thyroxine and triiodothyronine by rat-liver mitochondria.
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منابع مشابه
Stimulation of mitochondrial adenosine diphosphate uptake by thyroid hormones.
Thyroid hormone administered in vivo increased carrier-mediated (atractyloside-sensitive) ADP uptake by rat liver mitochondria. 3 Days after a single large dose of triiodothyronine (20 mug/100 g of body weight), mitochondrial uptake of ADP measured at 6 degrees was 2.35 +/- 0.17 nmol/min per mg of protein, compared with an uptake of 1.81 +/- 0.19 nmol/min per mg of protein in mitochondria from ...
متن کاملMetabolic effects of thyroid hormones in vitro. II. Influence of thyroxine and triiodothyronine on oxidative phosphorylation.
Because of the profound effect of thyroxine on the metabolic rates of animals, several groups of investigators have sought a relationship between this hormone and oxidative phosphorylation (14). The work in this laboratory was designed to test the hypothesis that the thyroid hormone may exert its salutary effects by uncoupling an oxidative phosphorylation just prior to a rate-limiting step in t...
متن کاملPropofol Attenuates Toxic Oxidative Stress by CCl4 in Liver Mitochondria and Blood in Rat
Anti-oxidant effects of propofol (2, 6-diisopropylphenol) were evaluated agains carbon tetrachloridet CCl4 -induced oxidative stress in rat liver. 30 male rats were equally divided in to 6 groups (5 rats each). Group I (control), while Group II was given CCl4 (3 mL /Kg/day, IP). Animals of Groups III received only propofol (10 mg/Kg/day, IP). Group IV was given propofol+ CCl4. Group V was admin...
متن کاملEvaluation of serum triiodothyronine and adjusted triiodothyronine (free triiodothyronine index) in pregnancy.
We measured serum thyroxine (free and total), triiodothyronine (free and total), thyroxine-binding globulin, and triiodothyronine uptake by talc in 97 normal men and 50 pregnant women. Mean serum thyroxine and triiodothyronine concentrations were higher in the pregnant subjects (104 vs. 78 mug/liter and 1.69 vs. 1.30 mug/liter) because of a higher mean thyroxine-binding globulin concentration (...
متن کاملThe concentration and binding of thyroxine and triiodothyronine by rat diaphragm.
Thyroid hormone has long been thought to exert its primary effect in the peripheral tissues. Recent studies have indicated, however, that thyroxine may be converted to other products in these tissues before becoming metabolically active (1-4). Whether or not a subsequent alteration is necessary, it seems probable that the thyroxine must first be fixed in some form of physicochemical union, eith...
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عنوان ژورنال:
- The Biochemical journal
دوره 60 1 شماره
صفحات -
تاریخ انتشار 1955